William R Schief: search on Z-Library

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1

Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope

Mihai L. Azoitei, Yih-En Andrew Ban, Jean-Philippe Julien, Steve Bryson, Alexandria Schroeter, Oleksandr Kalyuzhniy, Justin R. Porter, Yumiko Adachi, David Baker, Emil F. Pai, William R. Schief

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.79 MB

english, 2012

2

A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

Procko, Erik, Berguig, Geoffrey Y., Shen, Betty W., Song, Yifan, Frayo, Shani, Convertine, Anthony J., Margineantu, Daciana, Booth, Garrett, Correia, Bruno E., Cheng, Yuanhua, Schief, William R., Hock

Journal:

Year:

2014

Language:

english

File:

PDF, 3.35 MB

english, 2014

3

Glycoengineering HIV-1 Env creates ‘supercharged’ and ‘hybrid’ glycans to increase neutralizing antibody potency, breadth and saturation

Crooks, Ema T., Grimley, Samantha L., Cully, Michelle, Osawa, Keiko, Dekkers, Gillian, Saunders, Kevin, Rämisch, Sebastian, Menis, Sergey, Schief, William R., Doria-Rose, Nicole, Haynes, Barton, Murre

Journal:

Year:

2018

Language:

english

File:

PDF, 12.92 MB

english, 2018

4

ChemInform Abstract: Binding and Two-Dimensional Crystallization of Streptavidin at the Air/Water Interface via Engineered Cu-IDA Chelator Lipids

Kevin M. Maloney, William R. Schief Jr., Daniel W. Pack, Wolfgang Frey, Frances H. Arnold, Viola Vogel

Journal:

Year:

1999

File:

PDF, 26 KB

1999

5

Binding and two-dimensional crystallization of streptavidin at the air/water interface via engineered Cu-IDA chelator lipids

Kevin M Maloney, William R Schief Jr., Daniel W Pack, Wolfgang Frey, Frances H Arnold, Viola Vogel

Journal:

Coordination Chemistry Reviews

Year:

1999

Language:

english

File:

PDF, 669 KB

english, 1999

6

Light scattering microscopy from monolayers and nanoparticles at the air/water interface

William R Schief, Shelli R Dennis, Wolfgang Frey, Viola Vogel

Journal:

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Year:

2000

Language:

english

File:

PDF, 1.49 MB

english, 2000

7

Two-dimensional crystallization of streptavidin: in pursuit of the molecular origins of structure, morphology, and thermodynamics

William R Schief, Todd Edwards, Wolfgang Frey, Sandy Koppenol, Patrick S Stayton, Viola Vogel

Journal:

Biomolecular Engineering

Year:

1999

Language:

english

File:

PDF, 1.65 MB

english, 1999

8

High-resolution structure prediction of a circular permutation loop

Bruno E. Correia, Margaret A. Holmes, Po-Ssu Huang, Roland K. Strong, William R. Schief

Journal:

Protein Science

Year:

2011

Language:

english

File:

PDF, 579 KB

english, 2011

9

Rosetta predictions in CASP5: Successes, failures, and prospects for complete automation

Philip Bradley, Dylan Chivian, Jens Meiler, Kira M.S. Misura, Carol A. Rohl, William R. Schief, William J. Wedemeyer, Ora Schueler-Furman, Paul Murphy, Jack Schonbrun, Charles E.M. Strauss, David Bake

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2003

Language:

english

File:

PDF, 1.05 MB

english, 2003

10

Mapping a common interaction site used by Plasmodium falciparum Duffy binding-like domains to bind diverse host receptors

Dasein P.-G. Howell, Emily A. Levin, Amy L. Springer, Susan M. Kraemer, David J. Phippard, William R. Schief, Joseph D. Smith

Journal:

Molecular Microbiology

Year:

2008

Language:

english

File:

PDF, 705 KB

english, 2008

11

Conformational changes during kinesin motility

William R Schief, Jonathon Howard

Journal:

Current Opinion in Cell Biology

Year:

2001

Language:

english

File:

PDF, 131 KB

english, 2001

12

Molecular Motors: Single-Molecule Recordings Made Easy

Stefan Diez, William R Schief, Jonathon Howard

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 70 KB

english, 2002

13

Design and Characterization of Epitope-Scaffold Immunogens That Present the Motavizumab Epitope from Respiratory Syncytial Virus

Jason S. McLellan, Bruno E. Correia, Man Chen, Yongping Yang, Barney S. Graham, William R. Schief, Peter D. Kwong

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 1.85 MB

english, 2011

14

Dynamics of two-dimensional protein crystallization at the air/water interface: streptavidin targetted to surfaces via high-affinity binding or metal coordination

Viola Vogel, William R. Schief Jr, Wolfgang Frey

Journal:

Supramolecular Science

Year:

1997

Language:

english

File:

PDF, 3.42 MB

english, 1997

15

Discrepancy between Phase Behavior of Lung Surfactant Phospholipids and the Classical Model of Surfactant Function

Piknova, Barbora, Schief, William R., Vogel, Viola, Discher, Bohdana M., Hall, Stephen B.

Journal:

Biophysical Journal

Year:

2001

Language:

english

File:

PDF, 715 KB

english, 2001

16

Liquid-Crystalline Collapse of Pulmonary Surfactant Monolayers

Schief, William R., Antia, Meher, Discher, Bohdana M., Hall, Stephen B., Vogel, Viola

Journal:

Biophysical Journal

Year:

2003

Language:

english

File:

PDF, 1.24 MB

english, 2003

17

Learning from Nature to design new biomolecules

Jane Clarke, William Schief

Journal:

Current Opinion in Structural Biology

Year:

2012

Language:

english

File:

PDF, 154 KB

english, 2012

18

Electron Crystallographic Analysis of Two-Dimensional Streptavidin Crystals Coordinated to Metal-Chelated Lipid Monolayers

Frey, Wolfgang, Brink, Jacob, Schief, William R., Chiu, Wah, Vogel, Viola

Journal:

Biophysical Journal

Year:

1998

Language:

english

File:

PDF, 308 KB

english, 1998

19

Phase Separation in Monolayers of Pulmonary Surfactant Phospholipids at the Air–Water Interface: Composition and Structure

Discher, Bohdana M., Schief, William R., Vogel, Viola, Hall, Stephen B.

Journal:

Biophysical Journal

Year:

1999

Language:

english

File:

PDF, 633 KB

english, 1999

20

Advances in structure-based vaccine design

Kulp, Daniel W, Schief, William R

Journal:

Current Opinion in Virology

Year:

2013

Language:

english

File:

PDF, 1.95 MB

english, 2013

21

Computation-Guided Vaccine Design

Schief, William

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 34 KB

english, 2013

22

Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein

Bates, John T., Keefer, Christopher J., Slaughter, James C., Kulp, Daniel W., Schief, William R., Crowe, James E.

Journal:

Year:

2014

Language:

english

File:

PDF, 589 KB

english, 2014

23

Two-Dimensional Protein Crystallization Via Metal-Ion Coordination by Naturally Occurring Surface Histidines

Wolfgang Frey, William R. Schief, Daniel W. Pack, Chao-Tsen Chen, Ashutosh Chilkoti, Patrick Stayton, Viola Vogel and Frances H. Arnold

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.04 MB

english, 1996

24

Molecular Basis for Ionic Strength Dependence and Crystal Morphology in Two-Dimensional Streptavidin Crystallization

Edwards, Todd C., Koppenol, Sandy, Frey, Wolfgang, Schief,, William R., Vogel, Viola, Stenkamp, Ronald E., Stayton, Patrick S.

Journal:

Year:

1998

Language:

english

File:

PDF, 140 KB

english, 1998

25

Two-Dimensional Crystallization of Streptavidin Studied by Quantitative Brewster Angle Microscopy

Frey, Wolfgang, Schief, William R., Vogel, Viola

Journal:

Year:

1996

Language:

english

File:

PDF, 438 KB

english, 1996

26

Design and Characterization of Stabilized Derivatives of Human CD4D12 and CD4D1

Saha, Piyali, Barua, Bipasha, Bhattacharyya, Sanchari, Balamurali, M. M., Schief, William R., Baker, David, Varadarajan, Raghavan

Journal:

Year:

2011

Language:

english

File:

PDF, 1.94 MB

english, 2011

27

Investigating Epitope Exposure on Native Trimers

Menis, Sergey, Carrico, Chris, Kulp, Dan, Schief, William

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 61 KB

english, 2014

28

Refocussing Antibody Responses by Chemical Modification of Vaccine Antigens

Schiffner, Torben, Leonavicius, Karolis, Schuster, Heiko, Kim, Helen J., Kong, Leopold, Saliba, Regis, Brod, Florian, Wegmann, Frank, Huang, Po-Ssu, Stewart-Jones, Guillaume B., Schief, William R., Wa

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 85 KB

english, 2014

29

Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5

Azoitei, M. L., Ban, Y. A., Kalyuzhny, O., Guenaga, J., Schroeter, A., Porter, J., Wyatt, R., Schief, William R.

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2014

Language:

english

File:

PDF, 698 KB

english, 2014

30

Structure of HIV-1 gp120 with gp41-Interactive Region Reveals Layered Envelope Architecture and Basis of Conformational Mobility

Marie Pancera, Shahzad Majeed, Yih-En Andrew Ban, Lei Chen, Chih-Chin Huang, Leopold Kong, Young Do Kwon, Jonathan Stuckey, Tongqing Zhou, James E. Robinson, William R. Schief, Joseph Sodroski, Richar

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.62 MB

english, 2010

31

Glycan Masking of Plasmodium vivax Duffy Binding Protein for Probing Protein Binding Function and Vaccine Development

Sampath, Sowmya, Carrico, Chris, Janes, Joel, Gurumoorthy, Sairam, Gibson, Claire, Melcher, Martin, Chitnis, Chetan E., Wang, Ruobing, Schief, William R., Smith, Joseph D., Kazura, James W.

Journal:

Year:

2013

Language:

english

File:

PDF, 7.18 MB

english, 2013

32

Correction for Ingale et al., Hyperglycosylated Stable Core Immunogens Designed To Present the CD4 Binding Site Are Preferentially Recognized by Broadly Neutralizing Antibodies

Ingale, Jidnyasa, Tran, Karen, Kong, Leopold, Dey, Barna, McKee, Krisha, Schief, William, Kwong, Peter D., Mascola, John R., Wyatt, Richard T.

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 86 KB

english, 2015

33

Elicitation of structure-specific antibodies by epitope scaffolds

Gilad Ofek, F. Javier Guenaga, William R. Schief, Jeff Skinner, David Baker, Richard Wyatt, Peter D. Kwong and Wayne A. Hendrickson

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 2.05 MB

english, 2010

34

D105 Reverse engineering HIV vaccines

Schief, William R

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2013

Language:

english

File:

PDF, 6.37 MB

english, 2013

35

Immunogenicity of HIV-1 envelope glycoprotein oligomers

Forsell, Mattias NE, Schief, William R, Wyatt, Richard T

Journal:

Current Opinion in HIV and AIDS

Year:

2009

Language:

english

File:

PDF, 321 KB

english, 2009

36

Challenges for structure-based HIV vaccine design

Schief, William R, Ban, Yih-En Andrew, Stamatatos, Leonidas

Journal:

Current Opinion in HIV and AIDS

Year:

2009

Language:

english

File:

PDF, 748 KB

english, 2009

37

Residue-centric modeling and design of saccharide and glycoconjugate structures

Labonte, Jason W., Adolf-Bryfogle, Jared, Schief, William R., Gray, Jeffrey J.

Journal:

Journal of Computational Chemistry

Year:

2016

Language:

english

File:

PDF, 1.09 MB

english, 2016

38

Effects of partially dismantling the CD4 binding site glycan fence of HIV-1 Envelope glycoprotein trimers on neutralizing antibody induction

Crooks, Ema T., Osawa, Keiko, Tong, Tommy, Grimley, Samantha L., Dai, Yang D., Whalen, Robert G., Kulp, Daniel W., Menis, Sergey, Schief, William R., Binley, James M.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.09 MB

english, 2017

39

Biophysical and Structural Characterization of Antibody Responses to Malaria Antigens

Scally, Stephen, Bosch, Alexander, McLeod, Brandon, Triller, Gianna, Imkeller, Katharina, Murugan, Rajagopal, Rämisch, Sebastian, King, Rick, Schief, William, Wardemann, Hedda, Julien, Jean-Philippe

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 46 KB

english, 2017

40

Expression of complete SIV p27 Gag and HIV gp120 engineered outer domains targeted by broadly neutralizing antibodies in live rubella vectors

Virnik, Konstantin, Nesti, Edmund, Dail, Cody, Hockenbury, Max, Ni, Yisheng, Felber, Barbara K., Schief, William R., Berkower, Ira

Journal:

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

41

Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens

Abbott, Robert K., Lee, Jeong Hyun, Menis, Sergey, Skog, Patrick, Rossi, Meghan, Ota, Takayuki, Kulp, Daniel W., Bhullar, Deepika, Kalyuzhniy, Oleksandr, Havenar-Daughton, Colin, Schief, William R., N

Journal:

Year:

2017

Language:

english

File:

PDF, 7.07 MB

english, 2017

42

Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant

Guenaga, Javier, Dosenovic, Pia, Ofek, Gilad, Baker, David, Schief, William R., Kwong, Peter D., Karlsson Hedestam, Gunilla B., Wyatt, Richard T., Qiu, Jianming

Journal:

Year:

2011

Language:

english

File:

PDF, 1.95 MB

english, 2011

43

RosettaAntibodyDesign (RAbD): A general framework for computational antibody design

Adolf-Bryfogle, Jared, Kalyuzhniy, Oleks, Kubitz, Michael, Weitzner, Brian D., Hu, Xiaozhen, Adachi, Yumiko, Schief, William R., Dunbrack, Roland L., Ben-Tal, Nir

Journal:

PLoS Computational Biology

Year:

2018

Language:

english

File:

PDF, 8.59 MB

english, 2018

44

One‐step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock‐in mice

Lin, Ying‐Cing, Pecetta, Simone, Steichen, Jon M, Kratochvil, Sven, Melzi, Eleonora, Arnold, Johan, Dougan, Stephanie K, Wu, Lin, Kirsch, Kathrin H, Nair, Usha, Schief, William R, Batista, Facundo D

Journal:

The EMBO Journal

Year:

2018

Language:

english

File:

PDF, 2.14 MB

english, 2018

45

When designing vaccines, consider the starting material: the human B cell repertoire

Havenar-Daughton, Colin, Abbott, Robert K., Schief, William R., Crotty, Shane

Journal:

Current Opinion in Immunology

Year:

2018

Language:

english

File:

PDF, 403 KB

english, 2018

46

Automatically Fixing Errors in Glycoprotein Structures with Rosetta

Frenz, Brandon, Rämisch, Sebastian, Borst, Andrew J., Walls, Alexandra C., Adolf-Bryfogle, Jared, Schief, William R., Veesler, David, DiMaio, Frank

Journal:

Year:

2018

Language:

english

File:

PDF, 1.42 MB

english, 2018

47

Probing the Role of HIV Antigen Nanoscale Organization on B-Cell Activation with DNA Origami

Veneziano, Remi, Moyer, Tyson, Stone, Matthew B., Kumari, Sudha, Schief, William R., Bathe, Mark, Irvine, Darrell

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 43 KB

english, 2019

48

Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination

Boopathy, Archana V., Mandal, Anasuya, Kulp, Daniel W., Menis, Sergey, Bennett, Nitasha R., Watkins, Hannah C., Wang, Wade, Martin, Jacob T., Thai, Nikki T., He, Yanpu, Schief, William R., Hammond, Pa

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

Language:

english

File:

PDF, 1.08 MB

english, 2019

49

Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination

Boopathy, Archana V., Mandal, Anasuya, Kulp, Daniel W., Menis, Sergey, Bennett, Nitasha R., Watkins, Hannah C., Wang, Wade, Martin, Jacob T., Thai, Nikki T., He, Yanpu, Schief, William R., Hammond, Pa

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

File:

PDF, 1.08 MB

2019

50

Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles

Melo, Mariane, Porter, Ely, Zhang, Yuan, Silva, Murillo, Li, Na, Dobosh, Brian, Liguori, Alessia, Skog, Pat, Landais, Elise, Menis, Sergey, Sok, Devin, Nemazee, David, Schief, William R., Weiss, Ron,

Journal:

Molecular Therapy

Year:

2019

Language:

english

File:

PDF, 1.58 MB

english, 2019

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